Gene
arl3a
- ID
- ZDB-GENE-050417-368
- Name
- ADP ribosylation factor like GTPase 3a
- Symbol
- arl3a Nomenclature History
- Previous Names
-
- si:dkey-52k1.1
- zgc:110197
- Type
- protein_coding_gene
- Location
- Chr: 13 Mapping Details/Browsers
- Description
- Predicted to have GTP binding activity. Predicted to be involved in cilium assembly. Predicted to localize to cytoplasm and microtubule cytoskeleton. Human ortholog(s) of this gene implicated in Joubert syndrome and retinitis pigmentosa. Is expressed in neural tube; otic placode; and pronephric duct. Orthologous to human ARL3 (ADP ribosylation factor like GTPase 3).
- Genome Resources
- Note
- None
- Comparative Information
-
- All Expression Data
- 6 figures from Thisse et al., 2004
- Cross-Species Comparison
- High Throughput Data
- Thisse Expression Data
-
- MGC:110197 (4 images)
Wild Type Expression Summary
- All Phenotype Data
- No data available
- Cross-Species Comparison
- Alliance
Phenotype Summary
Mutations
Human Disease
| Disease Ontology Term | Multi-Species Data | OMIM Term | OMIM Phenotype ID |
|---|---|---|---|
| retinitis pigmentosa 83 | Alliance | Retinitis pigmentosa 83 | 618173 |
| Joubert syndrome 35 | 618161 |
Domain, Family, and Site Summary
Domain Details Per Protein
| Protein | Length | ADP-ribosylation factor-like protein 2/3 | P-loop containing nucleoside triphosphate hydrolase | Small GTPase superfamily, ARF/SAR type | Small GTP-binding domain |
|---|---|---|---|---|---|
|
UniProtKB:A0A2R8QI61
|
182 | ||||
|
UniProtKB:Q568N2
|
96 |
Interactions and Pathways
No data available
Plasmids
No data available